This is not the case. The body doesn’t get used to Parkinson’s medication at all. It is true that the medicine’s effect seems to decrease as the disease progresses. This has nothing to do with addiction , but more with the slow progression of the disease that causes the brain to produce less and less dopamine. In such cases, increasing the dose may be necessary. As a consequence, there may also be side effects that make it impossible to give an ideal dose. In the course of Parkinson's disease, there can also be symptoms that are not caused by the lack of dopamine; therefore, these symptoms do not improve with dopaminergic medication.